Grape seed extract is beneficial for a number of cardiovascular conditions and may help with a type of poor circulation (chronic venous insufficiency) reduces swelling caused by injury and helps with eye disease related to diabetes and high cholesterol. In particular, grape-related anti-tumor activity encompasses a wide array of biological mechanisms and cellular targets, eventually leading to inhibition of cell growth and to enhanced apoptosis in several cancer cell lines, including lung, colon, breast, bladder, leukemia and prostate tumors. It contains antioxidants. These are substances that protect cells from damage and may help prevent many diseases.